Logan M. Vlach

This study identifies a non-catalytic function of SETD2 in maintaining nuclear lamina stability and genome integrity through its N-terminus interactions.

This study shows that impaired oxidative phosphorylation, driven by NDUFA4L2, promotes EMT and metastasis in renal cell carcinoma by altering chromatin accessibility.

This study identifies that WDR5 WIN site inhibitors suppress ribosome protein gene transcription, induce nucleolar stress, and activate p53 in MLL-rearranged cancer cells, revealing a novel ribosome-directed anti-cancer mechanism.

This study identifies Bud13 as an RNA-binding protein that reduces intron retention in Irf7, enhancing type I interferon response and antiviral defense.