W. Kimryn Rathmell

This study identifies a non-catalytic function of SETD2 in maintaining nuclear lamina stability and genome integrity through its N-terminus interactions.

This study shows that impaired oxidative phosphorylation, driven by NDUFA4L2, promotes EMT and metastasis in renal cell carcinoma by altering chromatin accessibility.

This study profiles metabolites in renal cell carcinoma tissue and fluid to show that nutrient availability is more influenced by tissue-specific factors than tumor-driven changes.

This study shows that macrophages in Notch1+/- mice promote osteogenic calcification in aortic valves through STAT3 splicing changes and increased recruitment and polarization.