Jeffrey E. Segall

This paper introduces a microfluidic rheometer to measure tumor spheroid mechanics and invasiveness in a physiologically relevant setting, finding that tumor stiffness and viscoelastic properties correlate with invasiveness.

This study identifies CD44 as a key mediator of cell traction force generation in hyaluronic acid-rich extracellular matrices, showing its role in modulating collagen network mechanics and tumor invasion.

This study shows that KIF9 is essential for male fertility by regulating flagellar waveforms in ciliated cells, as KIF9 knockout males are sterile despite normal sperm motility.