Adam M. Szewczyk

This study shows that loss of myosin VI causes age-related mitochondrial dysfunction in heart ventricles, affecting structure, distribution, and quality control.

This study shows that 820 nm infrared light enhances mitochondrial BKCa channel activity in guinea pig cardiomyocytes through a redox-dependent mechanism.

This study shows that 820 nm near-infrared light activates mitochondrial BKCa channels and induces transcriptome remodeling in hippocampal neurons and glioma cells, contributing to neuroprotection.

This study identifies dibenzoylmethane (DBM) as a novel inhibitor of BKCa channels, showing it blocks the pore and alters ion dynamics, with structural features critical for activity.

This paper introduces a rapid method for isolating mitochondria from rodent cardiomyocytes with minimal contamination and high yield, preserving mitochondrial function for downstream applications.

This study shows red/near-infrared light activates mitochondrial large-conductance calcium-activated potassium channels in glioblastoma cells using patch-clamp techniques.

This study identifies mitoBKCa, a BKCa splice variant in mitochondria of breast cancer cells, showing it modulates energy production and promotes proliferation, suggesting it as a potential therapeutic target.