Zhengpeng Wan

This study generates functional endothelial cells from human iPSCs using ETV2 overexpression, enabling the creation of vascularized microphysiological models.

This study investigates vascular impairment in Rett syndrome by analyzing patient-derived endothelial cells and identifies miR126-3p as a mediator of vascular dysfunction.

This study shows that ether lipids in cancer cells regulate membrane properties to influence iron uptake, ferroptosis, and metastasis, offering a therapeutic target.

This study shows that long-term flow can maintain and remodel microvascular networks in a microphysiological system for 51 days, reducing inflammation and enabling vascular remodeling.

This paper develops a vascularized tumor model to study TAM recruitment and evaluates a multispecific antibody's effect on monocyte migration and TAM repolarization.