Scotland E. Farley

This study identifies STX, a non-steroidal estrogenic compound, as targeting mitochondrial VDAC2 to enhance bioenergetics and provide neuroprotection in hypothalamic POMC neurons.

This paper describes a protocol for profiling lipid-protein interactions using multifunctional lipid probes and provides methods for conjugate preparation and proteomic analysis.

The paper develops multifunctional derivatives of sphingosine and sphinganine to study their cellular roles, revealing distinct protein interactomes and spatiotemporal distributions.

The paper synthesizes three palmitic acid derivatives with diazirine at different positions and shows that end-position diazirines crosslink distinct protein subsets.

The paper systematically analyzes the sphingomyelin synthase family in C. elegans, identifying three SM synthases and one CPE synthase with distinct subcellular distributions.