Gaelen Guzman

This paper describes a protocol for profiling lipid-protein interactions using multifunctional lipid probes and provides methods for conjugate preparation and proteomic analysis.

This study identifies CD45 as a sialic acid-dependent binding partner of CD33, showing that their interaction contributes to Alzheimer's disease susceptibility through impaired microglial function.

The paper systematically analyzes the sphingomyelin synthase family in C. elegans, identifying three SM synthases and one CPE synthase with distinct subcellular distributions.