Carmen Choya-Foces

The paper shows that modifying ionic interactions with phospholipids prevents hypoxic adaptation by preserving inner mitochondrial membrane fluidity and CoQ transfer.

The paper identifies YAP1 and QSER1 as key regulators of developmental signaling pathways in the mammalian epiblast, showing their role in maintaining pluripotency and preventing excessive differentiation.

This study identifies TMEM65 as a regulator of NCLX-dependent mitochondrial calcium efflux, showing its role in preventing calcium overload and cell death in excitable tissues.

The paper uses systems biology to identify mitochondrial dysfunction and metabolic disruptions as key factors in HFpEF using a rat model.

This study shows that NCLX is necessary for HIF-1 stabilization and transcriptional activity during hypoxia, linking acute and medium-term hypoxic responses through mitochondrial signaling.