Kent W. Hunter

This paper identifies RRP1B as a stress-responsive regulator of RNA processing and splicing in breast cancer, showing its role in splicing programs and tumor aggressiveness.

This study shows that tRNA acetylation regulates stress signaling in mammals by affecting ribosome function and interacting with the Gcn2 kinase.

This study examines four mouse breast cancer models to show that oncogenic drivers influence metastasis-specific copy number variations and gene expression, while genetic background also plays a significant role.

The paper identifies Smarcd1 as a 'Goldilocks' metastasis modifier gene, showing that both high and low expression correlate with better clinical outcomes, while intermediate expression worsens survival in breast cancer.

This study shows that NAT10 loss reduces lung metastasis by disrupting enhancer organization through p300 mislocalization and altering gene transcription related to metastasis.