Alvaro Hobbs

This study investigates how booster immunizations affect germinal center (GC) clonality in mice, finding that refueling leads to clonal expansion rather than memory recruitment.

The paper investigates how antibodies from an ongoing immune response affect interclonal competition in germinal centers, finding that antibody feedback reduces clones recognizing the same epitopes as circulating antibodies.

This study investigates how pre-existing antibodies and memory T cell help influence the dynamics of recall germinal centers, showing that pre-existing antibodies suppress antigen binding while memory T cells enable B cells to access GCs despite low antigen binding.