Chyi‐Song Hsieh

This study shows that gut microbe-derived short-chain fatty acids reduce joint inflammation after alphavirus infection by modulating immune cell activity.

The paper identifies a microenvironment-driven neoantigen, C19S, in type 1 diabetes that activates persistent memory T cells through HLA-DQ8 recognition.

This study shows that early-life Cryptosporidium parvum infection in mice disrupts oral tolerance by altering regulatory T cell development and inducing TH1 immune responses to dietary antigens.

This study shows that RAG suppresses group 2 innate lymphoid cells (ILC2s), affecting their cytokine production and contributing to inflammation in atopic dermatitis.

This study shows that inhibiting goblet cell-associated antigen passages (GAPs) during enteric infection promotes mucosal humoral immunity by mobilizing plasma cells, but requires a second signal for full IgA secretion.