Chaodong Ding

This study identifies an ASXL3-thyroid hormone axis in parvalbumin interneurons that regulates autism-like behaviors and shows that early TH supplementation can reverse these effects in mice.

This study shows that AAV-mediated CSNK2B gene replacement in Csnk2b haploinsufficient mice rescues ASD-like phenotypes and restores EEG biomarkers, supporting its use as a translational readout for gene therapy.

This study shows that Srcap haploinsufficiency in mice causes autistic-like behaviors by reducing Satb2 expression, which can be reversed with Satb2 gene therapy.