Kiran Bhaskar

This study shows OTULIN regulates tau expression and RNA metabolism in neurons, with implications for Alzheimer's disease and tauopathies.

This study examines the neurometabolomic effects of wood smoke exposure in aged mice and evaluates the protective effects of anti-aging therapies.

The paper shows that pathological tau activates NF-κB in microglia and that a pT181-Qβ vaccine reduces NF-κB activity in tauopathy mice.

The paper identifies a calcium-dependent pathway involving ALIX that links lysosomal damage to stress granule formation, promoting cell survival in response to various stressors.

This study compares two VLP-based vaccines targeting different pTau epitopes, finding that the PHF1 vaccine reduces tau pathology and restores cognition better than the AT8 vaccine in a mouse model.

This study uses optogenetic control of TFEB to reduce pathological tau in human iPSC-neurons derived from AD patients.