Author

Jonathan P. Hulse

University of New MexicoORCID 0000-0001-6184-2058Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:proteomics· 1

Frequent Co-Authors

Kiran BhaskariD· 3 shared Bryce ChackerianiD· 2 shared Julianne PeabodyiD· 2 shared Amanda M. Barkley‐LevensoniD· 1 shared Andrew K. OttensiD· 1 shared Barry E. BleskeiD· 1 shared David P. ScieszkaiD· 1 shared Ed Barr· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersNeuroscience

Kiran BhaskarORCID

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3 papers

Recent·Most cited

Pharmacology & ToxicologyParticle and Fibre ToxicologyPeer-reviewedSep 1, 2025

NEUROMETABOLOMIC IMPACTS OF MODELED WILDFIRE SMOKE AND PROTECTIVE BENEFITS OF ANTI-AGING THERAPEUTICS IN AGED FEMALE C57BL/6J MICE

David P. Scieszka, Jonathan P. Hulse, Haiwei Gu…·Matthew J. Campen

This study examines the neurometabolomic effects of wood smoke exposure in aged mice and evaluates the protective effects of anti-aging therapies.

9 citations

mouseproteomics

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NeurosciencebioRxivPreprintMar 10, 2025

Pathological tau activates inflammatory nuclear factor-kappa B (NF-κB) and pT181-Qβ vaccine attenuates NF-κB in PS19 tauopathy mice

Karthikeyan Tangavelou, Shanya Jiang, Somayeh Dadras…·Kiran Bhaskar

The paper shows that pathological tau activates NF-κB in microglia and that a pT181-Qβ vaccine reduces NF-κB activity in tauopathy mice.

DOI 10.1101/2025.03.10.642500

mouseexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintApr 5, 2024

Virus-like particle (VLP)-based vaccine targeting tau phosphorylated at Ser396/Ser404 (PHF1) site outperforms phosphorylated S199/S202 (AT8) site in reducing tau pathology and restoring cognitive deficits in the rTg4510 mouse model of tauopathy.

Jonathan P. Hulse, Nicole M. Maphis, Julianne Peabody…·Kiran Bhaskar

This study compares two VLP-based vaccines targeting different pTau epitopes, finding that the PHF1 vaccine reduces tau pathology and restores cognition better than the AT8 vaccine in a mouse model.

1 citation

mouseexperimental assay

𝕏 PostBluesky