Author

Ismael Sospedra-Arrufat

Consejo Superior de Investigaciones CientíficasORCID 0000-0001-6079-578XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:mouse· 3 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Assay:ATAC-seq· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Approach:deep learning· 1

Frequent Co-Authors

Javier López-Rı́osiD· 3 shared Ana Alcaina-CaroiD· 2 shared Ana Fernández-MiñániD· 2 shared Axel ViseliD· 2 shared Gretel NusspaumeriD· 2 shared Holger HeyniD· 2 shared Irepan Salvador-MartíneziD· 2 shared Juan J. TenaiD· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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3 shared papersDevelopmental Biology

Javier López-Rı́osORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Developmental BiologybioRxivPreprintNov 9, 2026

Network inference at single-cell resolution reveals morphoregulatory divergence and multilayered buffering in limb evolution

Ana Alcaina-Caro, Ismael Sospedra-Arrufat, Virginie Tissières…·Javier Lopez-Rios

The paper compares gene regulatory networks in mouse and pig limb development to reveal conserved and divergent regulatory programs and mechanisms of developmental robustness.

DOI 10.64898/2026.11.07.765081

mouserat

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GenomicsNature CommunicationsPeer-reviewedAug 7, 2025

Uncovering Hidden Enhancers Through Unbiased In Vivo Testing

Brandon J. Mannion, Stella Tran, Ingrid Plajzer-Frick…·Len A. Pennacchio

The paper identifies hidden enhancers in mouse embryos that are not detected by conventional chromatin profiling methods, highlighting a significant gap in enhancer discovery.

16 citations

mouseChIP-seq

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Cell BiologyImmunology and Cell BiologyPeer-reviewedJan 7, 2024

The cellular landscape of the endochondral bone during the transition to extrauterine life

Alejandro Díaz Rueda, Irepan Salvador‐Martínez, Ismael Sospedra-Arrufat…·Gretel Nusspaumer

This study profiles the single-cell composition of murine endochondral bone during the perinatal transition, identifying fibroblastic clusters and dynamic interactions relevant to skeletogenesis and immune development.

DOI 10.1111/imcb.12718

mousescRNA-seq

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