Author

Katherine H. O’Toole

New England Biolabs (United States)ORCID 0000-0001-6180-7607Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:biophysical modeling· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Lana SalehiD· 2 shared Sean R. LundiD· 2 shared Auriane BouchetiD· 1 shared Harold W. BelliD· 1 shared Jesse D. PyleiD· 1 shared Mia L. DeSanctisiD· 1 shared Sabaa Belkadi· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 17 mutual co-author links

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2 shared papersBiochemistry

Lana SalehORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintAug 14, 2025

Discovery of T-dioxygenases in bacteriophages and identification of a subclass that is dependent on a regulator protein for oxidation

Katherine H. O’Toole, Auriane Bouchet, Mia L. DeSanctis…·Lana Saleh

The paper identifies T-dioxygenases in bacteriophages, revealing a subclass requiring a regulator protein for oxidation and structural insights into their function.

DOI 10.1101/2025.08.14.668559

bacteria (other)proteomics

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MicrobiologyCell ReportsPeer-reviewedAug 1, 2024

Virus-encoded glycosyltransferases hypermodify DNA with diverse glycans

Jesse D. Pyle, Sean R. Lund, Katherine H. O’Toole, Lana Saleh

The paper identifies virus-encoded glycosyltransferases that hypermodify DNA with diverse glycans, revealing new biosynthetic pathways and their potential roles in genome defense and host-pathogen interactions.

13 citations

bacteria (other)DNA methylation

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