Author
New England Biolabs (United States)ORCID 0000-0003-2629-9795Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Katherine H. O’Toole, Auriane Bouchet, Mia L. DeSanctis…·Lana Saleh
The paper identifies T-dioxygenases in bacteriophages, revealing a subclass requiring a regulator protein for oxidation and structural insights into their function.
Jesse D. Pyle, Sean R. Lund, Katherine H. O’Toole, Lana Saleh
The paper identifies virus-encoded glycosyltransferases that hypermodify DNA with diverse glycans, revealing new biosynthetic pathways and their potential roles in genome defense and host-pathogen interactions.
Romualdas Vaisvila, V. K. Chaithanya Ponnaluri, Zhiyi Sun…·Theodore B. Davis
EM-seq detects DNA methylation at single base resolution using less DNA than bisulfite sequencing, showing improved accuracy and reliability.
Zhiyi Sun, Romualdas Vaisvila, Laura-Madison Hussong…·Laurence M. Ettwiller
This paper introduces LR-EM-seq, an enzymatic deamination method for long-range methylation profiling of 5-mC and 5-hmC, achieving better-defined DMRs over 5 kb.