Author

Sean R. Lund

New England Biolabs (United States)ORCID 0000-0003-1656-7979Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2 Microbiology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:bacteria (other)· 2 Approach:biophysical modeling· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Katherine H. O’TooleiD· 2 shared Lana SalehiD· 2 shared Andrew F. GardneriD· 1 shared Auriane BouchetiD· 1 shared Harold W. BelliD· 1 shared Jackson A. BussiD· 1 shared Jesse D. PyleiD· 1 shared Mia L. DeSanctisiD· 1 shared

Activity by Year

2024-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersBiochemistry

Katherine H. O’TooleORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

BiochemistrybioRxivPreprintAug 14, 2025

Discovery of T-dioxygenases in bacteriophages and identification of a subclass that is dependent on a regulator protein for oxidation

Katherine H. O’Toole, Auriane Bouchet, Mia L. DeSanctis…·Lana Saleh

The paper identifies T-dioxygenases in bacteriophages, revealing a subclass requiring a regulator protein for oxidation and structural insights into their function.

DOI 10.1101/2025.08.14.668559

bacteria (other)proteomics

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BiochemistryPLoS ONEPeer-reviewedDec 2, 2024

High-throughput Kinetics using Capillary Electrophoresis and Robotics (HiKER) platform used to Study T7, T3, and Sp6 RNA Polymerase Misincorporation

Zachariah I. Carter, William B. O’Brien, Sean R. Lund, Andrew F. Gardner

The paper introduces HiKER, a high-throughput platform for measuring RNA polymerase kinetics, showing differences in misincorporation rates among T7, T3, and Sp6 RNAPs.

4 citations

proteomicsexperimental assay

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MicrobiologyCell ReportsPeer-reviewedAug 1, 2024

Virus-encoded glycosyltransferases hypermodify DNA with diverse glycans

Jesse D. Pyle, Sean R. Lund, Katherine H. O’Toole, Lana Saleh

The paper identifies virus-encoded glycosyltransferases that hypermodify DNA with diverse glycans, revealing new biosynthetic pathways and their potential roles in genome defense and host-pathogen interactions.

13 citations

bacteria (other)DNA methylation

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Synthetic BiologyACS Synthetic BiologyPeer-reviewedFeb 20, 2024

Highly parallelized construction of DNA from low-cost oligonucleotide mixtures using Data-optimized Assembly Design and Golden Gate

Sean R. Lund, Vladimir Potapov, Sean R. Johnson…·Nathan A. Tanner

The paper describes a method for efficiently constructing genes from low-cost oligonucleotide mixtures using Data-optimized Assembly Design and Golden Gate Assembly.

18 citations

experimental assay

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