Tanya J. Shaw

This study uses scRNA-seq to compare fibroblast subtypes in keloid and normal skin tissues with cultured fibroblasts, finding that some disease-associated features persist in vitro.

This study investigates the functional effects of ALK variants in neural crest cells, showing that ALKF1174L increases migration and cytoskeletal protrusions through GSK3 binding.

The paper investigates the effects of inflammatory soup on sensory neuron excitability using human and mouse models, finding minimal changes and suggesting that in vitro modeling of peripheral sensitization is complex.

This study develops and simulates a computational model to understand how cell properties affect collective alignment, finding optimal self-propulsion and overlap avoidance ratios, and the role of deformability and junctions.

This study shows keloid fibroblasts have heightened cytoskeletal tension and lysosomal exocytosis in response to mechanical cues, altering ECM remodeling.

The paper identifies polarisation effects in fluorescently labelled fibres and introduces a correction method to improve fibre alignment analysis.

The paper creates a multi-scale spatial atlas of healthy human skin and basal cell carcinoma using various omics and imaging techniques, revealing cell population localization and origins.