Author

Yogesh K. Gupta

The University of Texas at San Antonio Health Science CenterORCID 0000-0001-6372-5007Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Yogesh K. Gupta1 paper · The University of Texas Health Science Center at Houston

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1 Assay:structural biology· 1 Organism:virus· 1

Frequent Co-Authors

Shailee AryaiD· 2 shared An‐Ping LiniD· 1 shared Anurag MisraiD· 1 shared Carine JaafariD· 1 shared Gabriela Huelgas‐MoralesiD· 1 shared Jacob P. Ritter· 1 shared Jihane KhalifeiD· 1 shared Kenneth N. Holder· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMicrobiology

Shailee AryaORCID

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2 papers

Recent·Most cited

MicrobiologyStructurePeer-reviewedApr 11, 2025

Structural Insights into the Assembly and Regulation of 2'-O RNA Methylation by SARS-CoV-2 nsp16/nsp10

Anurag Misra, R. Rahisuddin, Manish Parihar…·Yogesh K. Gupta

This study presents a 2.4 Å crystal structure of the SARS-CoV-2 nsp16/nsp10 complex bound to Cap-1 RNA, revealing structural insights into its assembly and methylation mechanism.

6 citations

virusstructural biology

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Cancer BiologyScience AdvancesPeer-reviewedJul 12, 2024

IRF8-mutant B cell lymphoma evades immunity through a CD74-dependent deregulation of antigen processing and presentation in MHC CII complexes

Zhijun Qiu, Jihane Khalife, Purushoth Ethiraj…·Ricardo C.T. Aguiar

This study shows that IRF8 mutations in DLBCL lymphomas impair antigen processing and presentation by reducing CD74 and HLA-DM, leading to immune evasion and increased tumor burden.

28 citationstop 1%

humanbulk RNA-seq

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