Kelly Marie Hines

This study shows that exogenous antimicrobial straight-chain unsaturated fatty acids (SCUFAs) promote low-temperature growth of Staphylococcus aureus by altering membrane lipid composition and enhancing carotenoid production.

This paper investigates how S. aureus lipase activity remodels its own lipidome and host phospholipids, revealing preferences for specific lipid structures and impacts on membrane physiology and host signaling.

This study shows that SCFAs from commensal bacteria impair S. aureus growth and virulence by disrupting BCFA metabolism and increasing antimicrobial sensitivity.

This study shows that oleic acid alters S. aureus membrane lipid composition, increasing resistance to antimicrobial peptides by changing biophysical properties.

This paper demonstrates that MSC-EVs modulate microglia morphology and cytokine secretion, suggesting their therapeutic potential for neuroinflammation, and introduces a high-throughput morphological screening method for EV bioactivity.

This paper shows that Staphylococcus aureus uses exogenous unsaturated fatty acids to enhance growth at low temperatures through lipid remodeling and carotenoid production.

The paper screens MSC morphology in response to inflammatory priming to identify optimal conditions for EV production and microglia modulation in bioreactors.

This study shows that DHCR7 deficiency leads to oxysterol accumulation, causing premature neurogenesis and neuronal localization issues in SLOS, with GR as a potential therapeutic target.