Author

Sjoerd J. L. van Wijk

Goethe University FrankfurtORCID 0000-0001-6532-7651Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Organism:mouse· 1 Assay:organoid / primary culture· 1 Assay:proteomics· 1

Frequent Co-Authors

Alec Geßner· 1 shared Andreas WeigertiD· 1 shared Christian BehrendsiD· 1 shared Christoph Scheuer· 1 shared Denise Balta· 1 shared Ernst H. K. StelzeriD· 1 shared Francesco PampaloniiD· 1 shared Friederike ZunkeiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Alec Geßner

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cancer BiologySignal Transduction and Targeted TherapyPeer-reviewedJun 1, 2026

Inhibition of IAPs induces programmed cell death and inflammatory signaling in patient-derived metastatic breast cancer organoids

Kaja Nicole Wächtershäuser, Jana V. Schneider, Alec Geßner…·Sjoerd J. L. van Wijk

This study shows that Smac mimetics induce apoptosis in breast cancer organoids and that necroptosis, associated with inflammation, can be inhibited by LUBAC inhibitors.

1 citation

humanorganoid / primary culture

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Cell BiologyAutophagyPeer-reviewedJan 2, 2025

Linear ubiquitination at damaged lysosomes induces local NF-κB activation and controls cell survival

Laura Zein, Marvin Dietrich, Denise Balta…·Sjoerd J. L. van Wijk

This study shows that linear ubiquitination at damaged lysosomes activates NF-κB and promotes cell survival through lysophagy.

31 citationstop 2%

mousehuman

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