M.F. Garcia Parajo

The paper shows extracellular mechanical forces influence Golgi secretory function by modulating carrier biogenesis and exocytosis, with molecular determinants including microtubule acetylation and protein kinase D activity.

This study shows that both intrinsically disordered and structured domains of the Progesterone Receptor are required for transcriptional condensate formation and regulate distinct gene expression programs.

The paper develops a high-density, multi-color single-molecule mapping method to study viral-receptor interactions in living cells and finds coordinated receptor diffusion affects viral residence time and infectivity.

This paper discovers that Flipper, a membrane tension probe, can photosensitize singlet oxygen to alter membrane tension and lipid phase separation, enabling optical control of lipid raft formation.

The paper shows a progesterone derivative covalently bound to a phospholipid activates breast cancer cell signaling and gene regulation without entering the cell.

The paper uses super-resolution microscopy to show that integrin nanoclusters are spatially segregated within focal adhesions, suggesting coordinated activation through adaptor nanoclusters.