Juan Andres Torreno-Pina

This study shows that both intrinsically disordered and structured domains of the Progesterone Receptor are required for transcriptional condensate formation and regulate distinct gene expression programs.

The paper develops a high-density, multi-color single-molecule mapping method to study viral-receptor interactions in living cells and finds coordinated receptor diffusion affects viral residence time and infectivity.

The paper shows a progesterone derivative covalently bound to a phospholipid activates breast cancer cell signaling and gene regulation without entering the cell.