Vincent Béringue

This study shows non-fibrillar prion protein oligomers can transmit folding information during early assembly, challenging the classical fibril-end templating model.

This paper introduces PrP E219K as a new substrate for RT-QuIC that amplifies multiple human prion strains and enables discrimination between sporadic and variant CJD strains.

This paper develops a stochastic reaction-diffusion model to study prion spreading dynamics, showing how non-linear tissue responses and replication kinetics interact to explain strain-specific phenotypes and neuro-invasion.

This study shows CWD prions can infect humanized mice, leading to atypical symptoms and transmissible infectivity, suggesting zoonotic potential and possible human transmission.

The paper compares two prion growth models, showing that the detailed balance between PrPSc and suPrP can replace the induced-fragmentation model.

The paper shows that structurally diverse PrPSc assemblies complement each other to cross species barriers, supporting the quasi-species concept in prions.

This study investigates the structural convergence and diversification of PrPSc assemblies during prion replication, revealing a secondary templating pathway that explains structural diversification.