Rahul Chadda

This study shows phosphorylation of IGF2BP1 and IGF2BP3 at a conserved serine acts as a configurational switch, altering their RNA binding domain arrangements and affecting mRNA regulation.

This study shows that the lysosomal LRRC8 complex regulates lysosomal pH, morphology, and systemic glucose metabolism by affecting mTOR signaling and autophagic flux.

The paper identifies a novel tetrameric intermediate in the retroviral integration pathway using biochemical and biophysical methods.

This study uses single-molecule techniques to show that RPA partially wraps ssDNA and that phosphorylation at Ser-384 modulates this wrapping.

This paper describes fluorescently modified human RPA to study its dynamic interactions with ssDNA and other proteins.