Author
Broad InstituteORCID 0000-0001-6747-660XUnclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Gerardo E Zavala, José A Velilla, Richard M Walsh…·Rachelle Gaudet
The paper structures ZmaM, a type II peptidase-ABC transporter in B. cereus, showing it activates and exports zwittermicin A by coordinating peptidase and transporter modules.
Jared R. Mayers, Jack Varon, Ruixuan Zhou…·Emily P. Balskus
The paper identifies bacterially-derived N-acetylputrescine as a marker of severe gram-negative bloodstream infections and shows that inhibiting its synthesis reduces bacterial growth and antibiotic resistance.
Derek A. Wong, Zachary M. Shaver, Maria D. Cabezas…·Michael C. Jewett
This paper develops a cell-free platform combining CFPS and AlphaLISA to rapidly study and engineer PTM installing proteins for therapeutic applications.