Author

Karolina I. Smoląg

Lund UniversityORCID 0000-0001-6940-7130Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Assay:scRNA-seq· 2 Assay:spatial transcriptomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Alexander PietrasiD· 3 shared Crister P CebergiD· 3 shared Rebecca RosbergiD· 3 shared David LindgreniD· 2 shared Dimitra Manou· 2 shared Elinn JohanssoniD· 2 shared Jonas SjölundiD· 2 shared Kristian PietrasiD· 2 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Alexander PietrasORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintDec 22, 2025

Coevolution of neoplastic and non-neoplastic reactive astrocyte states converges on mesenchymal-like and injury-response programs during murine glioblastoma progression and post-radiotherapy recurrence

David Lindgren, Rebecca Rosberg, Karolina I. Smoląg…·Alexander Pietras

The paper maps transcriptional changes in astrocyte and tumor cell states during glioblastoma progression and recurrence, identifying reactive astrocyte-like tumor cells associated with radioresistance.

DOI 10.64898/2025.12.18.695184

mousescRNA-seq

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Cancer BiologybioRxivPreprintJul 12, 2025

Phenotypic Screening Identifies Flunarizine as an Inhibitor of Radiotherapy-Induced Astrocyte Reactivity with Therapeutic Potential in Glioblastoma

Pauline Jeannot, Rebecca Rosberg, David Lindgren…·Alexander Pietras

This paper identifies Flunarizine as a compound that inhibits radiation-induced astrocyte reactivity and improves survival in a glioblastoma model.

1 citation

mouseimaging

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Cancer BiologyJCI InsightPeer-reviewedAug 22, 2024

Hypoxia-induced Complement Component 3 Promotes Aggressive Tumor Growth in the Glioblastoma Microenvironment

Rebecca Rosberg, Karolina I. Smoląg, Jonas Sjölund…·Alexander Pietras

This study identifies hypoxia-induced complement component 3 (C3) as a driver of aggressive glioblastoma growth by promoting cell proliferation and radio-resistance.

44 citationstop 2%

humanbulk RNA-seq

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