Jonas Sjölund

The paper maps transcriptional changes in astrocyte and tumor cell states during glioblastoma progression and recurrence, identifying reactive astrocyte-like tumor cells associated with radioresistance.

This study identifies pericytes as a key paracrine signaling hub in glioblastoma that restrains tumor progression by modulating the tumor microenvironment and immune response.

The paper identifies ALK1-expressing tumor-associated macrophages in breast cancer metastases that contribute to immunosuppression and poor patient survival.

This study identifies hypoxia-induced complement component 3 (C3) as a driver of aggressive glioblastoma growth by promoting cell proliferation and radio-resistance.