Dina Malounda

This paper introduces a 3D ultrasound imaging method called Takoyaki to visualize contrast agents and reporter genes in living organisms, demonstrating its use in in vitro and in vivo settings.

The paper describes a modular method to create targeted gas vesicle protein nanoparticles using His-tagged antibody fragments and Ni-NTA functionalization, validated for PSMA targeting.

This paper introduces HAM-SVD, a method for ultrafast ultrasound imaging of gas vesicles that improves signal-to-background ratio compared to existing techniques.

This paper introduces a new ultrasound beamforming algorithm that improves image contrast and resolution while maintaining computational efficiency.

This paper introduces a drug delivery system using ultrasound to trigger release from hydrogels containing gas vesicles, demonstrating targeted delivery in a rat colitis model.

This study characterizes gas vesicles as cavitation nuclei for ultrasound therapy using passive acoustic mapping and finds that cavitation activity diminishes rapidly after the first pulse.

This study introduces harmonic xAM (HxAM) imaging to improve GV detection sensitivity and imaging depth in vivo.

This study investigates how gas vesicles interact with blood components and shows that surface modifications can alter these interactions to improve in vivo performance.

This paper introduces a genetically encoded ultrasonic calcium reporter (URoC) for noninvasive in vivo imaging of calcium signaling in mammals.

This study uses cryo-electron tomography to reveal the structure of Anabaena flos-aquae gas vesicles, showing how GvpA subunits form the shell and how GvpC provides structural reinforcement.

This paper introduces gas vesicles as ultrasound contrast agents to enhance transcranial hemodynamic functional ultrasound imaging of mouse brain activity.

This paper demonstrates the use of gas vesicles engineered to produce mechanical effects via ultrasound, enabling targeted cell lysis and therapeutic payload release in vitro, in cellulo, and in vivo.

This paper introduces a noninvasive method to control specific neural circuits using acoustically targeted chemogenetics, demonstrating its ability to modulate hippocampal neurons and affect memory formation in mice.