Przemysław Dutka

This paper introduces cryoSHIELDs, tunable peptides that improve cryo-EM sample preparation by modulating the air-water interface, enhancing particle distribution and complex integrity across multiple protein systems.

This paper develops scalable human neuron models of Alzheimer's disease to reveal mechanisms linking Tau fibrillization to synaptic dysfunction and identifies therapeutic targets.

This paper introduces sono-uncaging, a method using ultrasound to control chemical reactivity in opaque materials, demonstrating spatial patterning with a diagnostic imaging transducer.

This study uses cryo-EM and single-molecule FRET to show conformational coupling between the extracellular and transmembrane domains of an aGPCR, revealing how ECR dynamics influence receptor function.

The paper evolves acoustic reporter genes using high-throughput acoustic screening to enhance nonlinear ultrasound scattering.

This paper introduces bicones, tiny acoustic contrast agents based on gas vesicles, showing their effectiveness in imaging and therapy through ultrasound.

This paper introduces a bioorthogonal labeling method to fluorescently visualize gas vesicles in cells, enabling analysis of their size and distribution.

This paper introduces a genetically encoded ultrasonic calcium reporter (URoC) for noninvasive in vivo imaging of calcium signaling in mammals.

This study uses cryo-electron tomography to reveal the structure of Anabaena flos-aquae gas vesicles, showing how GvpA subunits form the shell and how GvpC provides structural reinforcement.