Qi Wen

The paper shows that growth-mediated compressive stresses drive millimeter-scale gap closure in MEC1 cells, with fluid-like tissue remodeling enhancing collective closure.

This study decouples bulk stiffness and pore size in 3D collagen matrices and shows that changes in pore size affect cell morphology despite similar mechanical conditions.

This study reports cryo-EM structures of GGCX bound to VKDPs and vitamin K, revealing its dual-catalytic mechanism and disease-associated mutation clusters.

This study investigates how DDR2 affects cell mechanics and migration in neuroblastoma cells, finding that DDR2 down-regulation reduces proliferation, stiffness, and traction forces.

This study investigates how DDR2 and substrate stiffness affect cancer cell proliferation and transcriptome, revealing distinct regulatory mechanisms.

This study identifies TrpA1 as a shear stress sensor in Drosophila enteroendocrine cells that regulates intestinal stem cell activity and tissue homeostasis.