Alex B. Costa

The paper identifies a pathway involving Smc5/6 and Rtt107 that promotes palindrome-mediated genome instability through cruciform formation and cleavage.

This paper demonstrates the directed evolution of the Saccharomyces cerevisiae mitochondrial translation system as an orthogonal system to the cytosolic TS, revealing functional dependencies and enabling translation engineering.

This study identifies a dominant any1 mutation that confers strong canavanine resistance in fission yeast, enabling its use as a genetic selection marker.