Canavanine-based assay for gross chromosomal rearrangements reveals genome instability hotspots and modulating genes in fission yeast
Anissia Ait Saada, Cassandre Ollivier, Alex B. Costa…·Kirill S. Lobachev
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Centre National de la Recherche ScientifiqueORCID 0000-0002-1302-9246Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
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Anissia Ait Saada, Cassandre Ollivier, Alex B. Costa…·Kirill S. Lobachev
Alex B. Costa, Anissia Ait Saada, Thy Pham…·Kirill S. Lobachev
The paper identifies a pathway involving Smc5/6 and Rtt107 that promotes palindrome-mediated genome instability through cruciform formation and cleavage.
Kamila Schirmeisen, Karel Naiman, Karine Fréon…·Sarah Lambert
The paper investigates how SUMO protease and proteasome recruitment at nuclear pores affects replication dynamics at arrested forks in fission yeast.
Anissia Ait Saada, Alex B. Costa, Kirill S. Lobachev
This study identifies a dominant any1 mutation that confers strong canavanine resistance in fission yeast, enabling its use as a genetic selection marker.
Julien Hardy, Dingli Day, Anissia Ait Saada…·Sarah Lambert
The paper shows that histone deposition is essential for completing recombination-dependent replication (RDR) and balancing genome stability during replication stress in fission yeast.
Ana Teixeira-Silva, Anissia Ait Saada, Julien Hardy…·Sarah Lambert
The paper investigates how Ku coordinates fork resection and restart in Schizosaccharomyces pombe, revealing a two-step resection process and the role of Ku in fine-tuning HR-mediated replication restart.