Tobias Schmidt

This study identifies Pfk2p as an ATP-dependent RNA unwinding enzyme that modulates cell cycle progression by promoting translation of mitotic genes.

This study identifies how eIF4A1 differentially activates translation based on mRNA features, revealing distinct mechanisms for mRNA selection and inhibition by eFT226 and hippuristanol.

This study shows that DTX3L ubiquitinates single-stranded DNA and RNA, expanding the known substrates of ubiquitination beyond proteins.

The paper shows that eIF4A2, a negative regulator of mRNA translation, promotes ECM deposition to accelerate HCC initiation by influencing integrin-mediated signaling and senescence exit.

The paper identifies AG-rich RNA sequences in 5'UTRs that regulate eIF4A1 multimerisation to enhance translation of oncogenic mRNAs.