Author

Achim Schmidtko

Goethe University FrankfurtORCID 0000-0001-7270-5075Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Ruirui LuiD· 2 shared Amelie TjadeniD· 1 shared Andreas LeffleriD· 1 shared Annika Balzulat· 1 shared Annika FrankiD· 1 shared Bushra DohaiiD· 1 shared Cathrin Flauaus· 1 shared Chung‐Wen LiniD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersNeuroscience

Ruirui LuORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintJun 25, 2025

CaV1.2-dependent excitation-transcription coupling modulates nociception

Jörg Isensee, Patrick Engel, Paul Chu Sin Chung…·Tim B. Hucho

This paper investigates Cav1.2-dependent excitation-transcription coupling in nociceptors, showing it modulates pain sensitivity by affecting gene expression and neuronal function.

DOI 10.1101/2025.06.25.661480

mousebulk RNA-seq

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Pharmacology & ToxicologyAdvanced SciencePeer-reviewedFeb 13, 2024

Discovery of a new activator of Slack potassium channels with robust efficacy in models of histamine-independent and chronic itch

Annika Balzulat, Wenyong Zhu, Cathrin Flauaus…·Achim Schmidtko

This study identifies compound 6 as a potent Slack potassium channel activator effective in treating histamine-independent and chronic itch without motor side effects.

12 citations

mouseexperimental assay

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