Author
University of CambridgeORCID 0000-0001-7342-9295Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Sina Türeli, Theo M. Bestebroer, Sarah James…·Derek J. Smith
This paper introduces a high-throughput pipeline for selective mutational scanning in influenza viruses, enabling rapid assessment of variant fitness and escape potential.
Adinda Kok, Samuel H. Wilks, Sina Türeli…·Mathilde Richard
The paper creates a high-resolution antigenic map of A(H5) HA and uses it to design vaccine antigens that confer broad immunity against diverse A(H5) viruses.
Annika Rössler, Antonia Netzl, Ludwig Knabl…·Janine Kimpel
This study compares neutralizing antibody titers in human and hamster sera against SARS-CoV-2 variants using a live-virus neutralization assay, finding hamster sera show higher reactivity.
Barbara Mühlemann, Samuel Wilks, Lauren Baracco…·Derek J. Smith
The paper compares SARS-CoV-2 antigenicity across assays and in human and animal model sera, finding similar immunodominance patterns and antigenic maps but differences in titer magnitude and assay-specific fold change.
The paper uses stochastic calculus on elastic network models to analyze allostery by identifying functional sites through time-delayed residue correlations in three proteins.