Robert Z. Zhang

This study identifies viral determinants that influence neutralizing antibody production through a noncanonical pathway in gammaretroviral infections.

The paper shows that mice can control retroviral infection without TLR7 signaling, suggesting an alternative sensing pathway for immune activation.

This study shows that MX2 antiviral activity depends on CypA-CA interactions and GTPase function, with loss of GTPase activity altering Nup requirements for viral restriction.