Mehdi Kabani

This study uses an AAV model to show that aggregation-prone tau variants spread more extensively in the mouse brain, suggesting extracellular vesicles may contribute to tau propagation.

This study uses single molecule localization microscopy to detect pathological Tau proteins in extracellular vesicles from Alzheimer's disease brains.

This study shows that activating the JAK2-STAT3 pathway in astrocytes reduces mutant Huntingtin aggregates and improves disease outcomes in Huntington's disease models.