Ann Chahroudi

This study compares acute infection and viral rebound dynamics in ART-treated infant rhesus macaques using a mathematical model to identify increased infected cell death during rebound.

This study quantifies AZD5582's effect on SIV reservoirs in macaques, showing it reactivates 25% of latent cells per dose and clears 60-79% of reactivated cells.

This study investigates the effects of postnatal Zika virus infection in infant macaques, finding altered neurodevelopment, increased emotional reactivity, and changes in CSF volume and brain structure.

This study investigates the effects of Zika virus infection on infant brain development using single-cell transcriptomics and other methods, identifying disrupted pathways and behavioral changes.

This study evaluates a triple bNAb combination in infant rhesus macaques, showing durable neutralization and effector functions with high predicted prevention efficacy against HIV strains.

This study examines how early ART initiation in HIV-infected infants affects antibody development and latent reservoir dynamics, showing their opposing impacts on post-treatment viral rebound.

This study shows that postnatal Zika virus infection in infant macaques leads to long-term behavioral, motor, and cognitive deficits along with structural and functional brain changes.