Samir Merabet

The paper introduces a method to identify drug-sensitive protein-protein interactions in live cells using ERK1 as a case study, showing how inhibitory molecules affect these interactions.

The paper investigates how the Drosophila Hox factor Ultrabithorax uses DNA and RNA binding to regulate splicing and homeotic functions through homodimerization and specific amino acid interactions.

The paper investigates how the Drosophila posterior Hox protein Abd-B interacts with Exd and Hth cofactors in different developmental contexts, revealing context-dependent synergistic or antagonistic functional relationships.

The paper introduces a nanobody-based method to capture and visualize binary protein complex interactions in living cells, identifying new regulators of TAZ activity.

The paper discusses the Cell-PCA screen's role in analyzing cellular interactomes and identifies areas for optimization to maintain its relevance with advancing biotechnology.

The paper identifies a micro-evolutionary change in Ubx binding sites as a determinant of differential Ubx function between Drosophila and Apis mellifera.

The paper introduces Cell-PCA, a live cell protein complementation assay, to probe human HOX interactomes, revealing novel cofactors and molecular properties.

The paper identifies a versatile peptide motif in Drosophila Hox proteins that mediates nuclear export and autophagy regulation.

The paper introduces a multicolor BiFC library for studying protein-protein interactions in live Drosophila using Hox proteins as a case study.