Sandrine Hughes

This study shows that transposable elements (TEs) in Drosophila melanogaster cause phenotypic variation and affect responses to environmental changes.

This study identifies how epithelial morphogens guide stepwise mesodermal specification to generate muscle diversity in Drosophila leg development.

The paper introduces a method to identify drug-sensitive protein-protein interactions in live cells using ERK1 as a case study, showing how inhibitory molecules affect these interactions.

This study shows that juvenile protein restriction in mice reduces sexual dimorphism by affecting somatic growth, energy metabolism, and hepatic molecular identity, with distinct adaptations in reproductive development.

This study uses long-read RNA-seq to identify and quantify transposable element transcripts at the copy level in Drosophila germline tissues, revealing differences in their transcriptional landscape between testes and ovaries.

The paper identifies a shared neoepitope from non-canonical c-MYC translation in cancer cells that activates T cells to kill tumors without harming normal cells.

This study identifies AtVPS13M1 as a lipid transporter in Arabidopsis thaliana that affects phospholipid degradation during phosphate starvation and localizes to mitochondria.

The paper discusses the Cell-PCA screen's role in analyzing cellular interactomes and identifies areas for optimization to maintain its relevance with advancing biotechnology.

The paper identifies Collagen XV-B and Tenascin C as ECM components guiding motor axon growth through their dual topology and stiffness in zebrafish.

The paper examines gene expression coordination between host and endosymbiont during the life cycle of the cereal weevil, identifying shared regulatory functions involved in symbiosis dynamics.

The paper introduces Cell-PCA, a live cell protein complementation assay, to probe human HOX interactomes, revealing novel cofactors and molecular properties.

This study compares gene expression dynamics during leg development and regeneration in Parhyale hawaiensis, finding distinct temporal patterns despite shared gene sets.

The paper presents the genome of Sitophilus oryzae, revealing high transposable element content and host-symbiont metabolic interactions.

This study analyzes 54 Lactobacillus plantarum genomes to show that their genome evolution is not tied to specific environmental niches, suggesting a nomadic lifestyle.