Author

Alison Burgess Hickman

National Institutes of HealthORCID 0000-0001-7666-0249Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:protein design· 1 Assay:protein structure· 1 Assay:structural biology· 1

Frequent Co-Authors

Fred DydaiD· 3 shared Alexandria Primich· 1 shared Anna Menshikh· 1 shared Astrid D. Desiree HaaseiD· 1 shared Christopher D. BahliD· 1 shared Christopher M. FurmaniD· 1 shared Dean R. MaddeniD· 1 shared Kelli L. HvorecnyiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersMolecular Biology

Fred DydaORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJul 16, 2026

Structure-based recasting of a mammalian DNA transpososomeas an obligate heterodimer

Raju Mandal, Alison Burgess Hickman, Rhea Desai…·Fred Dyda

The paper determines the structure of a hyperactive transpososome and engineers an obligate heterodimeric system for targeted genomic integration.

DOI 10.64898/2026.07.15.738711

mouseprotein structure

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BiochemistrybioRxivPreprintJan 16, 2024

Molecular basis for the transcriptional regulation of an epoxide-based virulence circuit in Pseudomonas aeruginosa

Susu He, Noor M. Taher, Kelli L. Hvorecny…·Dean R. Madden

This study identifies the molecular mechanisms by which CifR, an epoxide-sensing transcriptional repressor, regulates the virulence gene cif in Pseudomonas aeruginosa.

DOI 10.1101/2024.01.16.572601

bacteria (other)structural biology

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Molecular BiologyNucleic Acids ResearchPeer-reviewedDec 7, 2022

Transposase N-terminal phosphorylation and asymmetric transposon ends inhibit piggyBac transposition in mammalian cells

Wentian Luo, Alison Burgess Hickman, Pavol Genzor…·Matthew H. Wilson

This study investigates how N-terminal phosphorylation and asymmetric transposon ends regulate piggyBac transposition in mammalian cells, revealing mechanisms that inhibit the process.

13 citations

mouseexperimental assay

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