Fred Dyda

The paper determines the structure of a hyperactive transpososome and engineers an obligate heterodimeric system for targeted genomic integration.

The paper evaluates crystal diffraction data quality metrics, finding that low-shell values of Rmerg, Rmeas, Rpim, and CC1/2 indicate Laue symmetry correctness, while high-shell I/σI is better for resolution cutoff selection.

This study identifies the molecular mechanisms by which CifR, an epoxide-sensing transcriptional repressor, regulates the virulence gene cif in Pseudomonas aeruginosa.

This study investigates how N-terminal phosphorylation and asymmetric transposon ends regulate piggyBac transposition in mammalian cells, revealing mechanisms that inhibit the process.