Author

Harald Hornegger

University of ViennaORCID 0000-0001-7703-9710Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:metagenomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Gülsün Elif KaragöziD· 3 shared Aleksandra S. AnisimovaiD· 2 shared Gijs A. VersteegiD· 2 shared Adnan MuratoviciD· 1 shared Benjamin M. R. BourgeoisiD· 1 shared Daniel B. GrabarczykiD· 1 shared David HaselbachiD· 1 shared Elena SpinettiiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersCell Biology

Gülsün Elif KaragözORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cell BiologyGenes & DevelopmentPeer-reviewedJul 23, 2026

Dual regulation of the unfolded protein response by IGF2BP3 during ER stress

Aleksandra S. Anisimova, Sabina Omerbegovic, Milica Mihailović…·Gülsün Elif Karagöz

This study shows IGF2BP3 regulates UPR effectors by stabilizing transcriptional regulators and destabilizing UPR target mRNAs during ER stress, modulating the UPR response.

DOI 10.1101/gad.353291.125

metagenomicsexperimental assay

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Cell BiologyNature CommunicationsPeer-reviewedJan 19, 2026

Guardian ubiquitin E3 ligases target cancer-associated APOBEC3 deaminases for degradation to promote human genome integrity.

Irene Schwartz, Valentina Budroni, Mathilde Meyenberg…·Gijs A. Versteeg

The paper identifies UBR4, UBR5, and HUWE1 as E3 ligases that degrade cancer-associated APOBEC3 proteins to prevent genome mutagenesis.

9 citationstop 3%

humanproteomics

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BiochemistryNature CommunicationsPeer-reviewedOct 19, 2024

IGF2BP1 phosphorylation regulates ribonucleoprotein condensate formation by impairing low-affinity protein and RNA interactions

Harald Hornegger, Aleksandra S. Anisimova, Adnan Muratovic…·Gülsün Elif Karagöz

This study shows that phosphorylation of IGF2BP1 at S181 and Y396 modulates RNP condensate formation by altering low-affinity interactions with RNA and protein partners.

13 citations

humanproteomics

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