Aleksandra S. Anisimova

This study shows IGF2BP3 regulates UPR effectors by stabilizing transcriptional regulators and destabilizing UPR target mRNAs during ER stress, modulating the UPR response.

The paper identifies a retrograde signaling pathway where UFMylation of ER ribosomes anchors splicing factors at the ER, linking translational stress to nuclear RNA processing and altering membrane-associated gene expression.

This study identifies EDC4 and DCP1 as autophagy receptors for P-body turnover in Marchantia polymorpha, revealing lineage-specific adaptations and potential therapeutic applications.

The paper shows UFMylation and RQC work together to clear stalled ER-bound ribosomes and arrested nascent chains.

This study shows that phosphorylation of IGF2BP1 at S181 and Y396 modulates RNP condensate formation by altering low-affinity interactions with RNA and protein partners.

The paper analyzes transcriptomic and proteomic data to identify tissue-specific expression of translation machinery components and highlights sexual dimorphism in translation factors.

This study examines age-related changes in the transcriptome and translatome of mouse tissues, revealing U-shaped gene expression patterns and age-related declines in protein synthesis.

The paper uses comparative morphology and molecular genetics to study East European Unionidae mussels, finding that genetic methods better resolve species than morphology.