BiophysicsScience AdvancesPeer-reviewed
In situ structural insights into the excitation contraction coupling mechanism of skeletal muscle
Jiashu Xu, Chenyi Liao, Changcheng Yin…·Fei Sun
This study reveals the nanometre-resolution structure of the RyR1-DHPR supercomplex in skeletal muscle triads, showing their unique arrangement and physical coupling mechanism for excitation-contraction coupling.
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