Author

Michael J. Metzger

University of WashingtonORCID 0000-0001-7855-1388Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1 Ecology· 1 Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 5 Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:Drosophila· 1

Frequent Co-Authors

Fiona E. S. GarrettiD· 4 shared Jordana K. SevignyiD· 3 shared Marisa A. YonemitsuiD· 3 shared Rachael M. GierschiD· 3 shared Samuel F. M. HartiD· 3 shared Sydney A. WeinandtiD· 3 shared Elizabeth Unsell· 2 shared James L. DimondiD· 2 shared

Activity by Year

2021-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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4 shared papersCancer Biology

Fiona E. S. GarrettORCID

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

EcologyProceedings of the National Academy of SciencesPeer-reviewedJun 23, 2026

Identification of an Outbreak of Bivalve Transmissible Neoplasia in Soft-Shell Clams (Mya arenaria) in the Puget Sound Using Hemolymph and eDNA Surveys

Sydney A. Weinandt, Zachary J. Child, Dorothy Lartey…·Michael J. Metzger

The paper identifies a new outbreak of transmissible cancer in soft-shell clams in Puget Sound using eDNA surveys and shows the disease originated from a distant location.

4 citationstop 5%

bacteria (other)metagenomics

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Cancer BiologyPLoS PathogensPeer-reviewedSep 29, 2025

Variation in Natural Infection Outcomes and Cancer Cell Release from Soft-Shell Clams (Mya arenaria) with Bivalve Transmissible Neoplasia

Rachael M. Giersch, Jordana K. Sevigny, Sydney A. Weinandt…·Michael J. Metzger

This study tracks BTN progression in soft-shell clams, showing variable outcomes and cancer cell release into seawater above 24% hemolymph cancer levels.

3 citations

bacteria (other)DNA methylation

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GenomicsPLoS GeneticsPeer-reviewedMar 31, 2025

Gene expression in soft-shell clam (Mya arenaria) transmissible cancer reveals survival mechanisms during host infection and seawater transfer

Samuel F. M. Hart, Fiona E. S. Garrett, Jesse S. Kerr, Michael J. Metzger

5 citations

bacteria (other)bulk RNA-seq

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Cancer BiologyMolecular EcologyPeer-reviewedFeb 20, 2025

Multiple lineages of transmissible neoplasia in the basket cockle (Clinocardium nuttallii) with repeated horizontal transfer of mitochondrial DNA

Marisa A. Yonemitsu, Jordana K. Sevigny, Lauren E. Vandepas…·Michael J. Metzger

The paper identifies two lineages of transmissible neoplasia in basket cockles, with one lineage showing repeated horizontal transfer of mitochondrial DNA.

11 citationstop 1%

bacteria (other)experimental assay

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Cell BiologybioRxivPreprintJun 28, 2023

A rapid, inexpensive, non-lethal method for detecting disseminated neoplasia in a bivalve

Lauren E. Vandepas, Ryan N. Crim, Emily Gilbertson…·Frederick W. Goetz

This paper presents a non-lethal, rapid, and low-cost method for detecting disseminated neoplasia in basket cockles, validated against histology with high accuracy.

DOI 10.1101/2023.06.28.544680

bacteria (other)experimental assay

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GeneticsPLoS GeneticsPeer-reviewedApr 22, 2021

Intercellular viral spread and intracellular transposition of Drosophila gypsy

Richard M. Keegan, Lillian R. Talbot, Yung‐Heng Chang…·Josh Dubnau

This study shows Drosophila gypsy retrotransposon can replicate via both intracellular retrotransposition and intercellular viral spread, depending on the presence of its envelope protein.

14 citations

Drosophilaexperimental assay

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