Stuart J. Hesketh

This study shows that morning endurance training in mice leads to better performance adaptations than afternoon training, despite lower training volumes.

This study shows that morning caffeine ingestion improves neuromuscular performance in females, matching evening levels by increasing peak force and time to exhaustion.

This study identifies changes in the skeletal muscle nuclear proteome after acute exercise, revealing post-transcriptional effects on mRNA processing and splicing.

This study quantifies skeletal muscle proteome changes over time in rats during resistance training, revealing distinct adaptation phases driven by ribosomal and mitochondrial protein dynamics.

This study shows that BMAL1 in skeletal muscle is essential for transcriptional responses to exercise and peripheral tissue adaptations, with its loss leading to divergent transcriptomic and metabolomic changes and increased inflammation.

This study identifies age-dependent and tissue-specific changes in the circadian transcriptome of male mice, showing reduced rhythmic gene expression and increased variability in aged tissues.