Advait Athreya

This study uses molecular dynamics simulations to show that spacer heterogeneity in stickers-and-spacers polymers promotes condensation but reduces condensate organization and compositional robustness.

This study shows that single nucleosomes encode A/B compartment information through biophysical properties, specifically condensability, which correlates with gene expression and is electrostatic in nature.

This study reanalyzes Brd2 depletion effects on chromatin compartments using Micro-C data and cooltools, showing persistent but reduced compartment strength changes.

The paper identifies a SIRT6 variant enriched in centenarians that improves genome stability through enhanced mADPr activity and interaction with Lamin A.